Levosin and Levomekol are antimicrobial drugs for topical use, which are very popular on the Russian pharmaceutical market. The difference between Levosin and Levomekol is in many ways.
Which ones, and which drug is better – let’s try to figure out the article.
Levosin: pharmacological properties
To find out which is better: Levosin or Levomekol, it is necessary to elaborate on each drug in more detail. Levocin is an antibacterial ointment containing several active antimicrobial substances: levomycetin, sulfanilamide, methyluracil.
The ointment is produced by various pharmaceutical companies in vials or packs of soft aluminum.
The main pharmacological effect is antimicrobial and anti-inflammatory. The tool is applied to the wound surface, well contributes to the purification and removal of necrotic masses, accelerates healing, the formation of fibrin tissue.
Due to the content in the composition of antibacterial components, Levocin effectively fights with the local pathogenic flora sensitive to the antibiotics listed above.
Pharmacokinetic parameters associated with the feature of the dosage form. The ointment acts only when applied locally, the ingress of active ingredients into the systemic circulation is minimal.
Toxic effects on the kidneys and liver are excluded. Levosin is recommended for patients who have not taken levomycetin, sulfonamides, methyluracil in the next six months.
Otherwise, the sensitivity to the drug may be reduced.
The main indications for the use of Levosin:
- Purulent wound infections;
- Scratches, wounds of various etiologies;
- Ulcers of the lower limbs;
The range of contraindications to use:
- Viral etiology wounds;
- Increased sensitivity of the body to the components of an antimicrobial agent.
Adverse reactions are minimal and are associated with allergic manifestations when re-applying the ointment. If signs of allergy appear, it is recommended to replace the ointment or consult a doctor to prescribe a systemic drug.
Ointment Levosin should be applied to the skin and wound surfaces with sterile material twice a day for a week. Perhaps the introduction of ointment in purulent cavities through the drainage. With this use Levosin should be heated to body temperature.
The course of treatment may be extended according to indications, but should last at least a week.
Before applying Levosin, primary wound surgery is performed, dead tissues are removed, the defect is washed with antiseptics. After using the ointment, apply a sterile dressing.
Levomekol: pharmacological properties
Comparison of Levomekol and Levosin can be carried out by the main parameters: pharmacological properties, pharmacokinetics, composition, indications, contraindications, adverse reactions, application rules. Levomekol is a drug similar to Levosin in its mechanism of action and effect.
Ointment Levomekol – the combined antibacterial agent. The spectrum of activity includes gram-positive and negative microbes, including the pyocyanic stick.
Levomekol promotes the regeneration of affected tissues, eliminates bacteria, stimulates the formation of macrophages and neutrophils. Ointment is also applied externally. Absorption from the surface of the skin into the systemic circulation is minimal.
Toxic effects means on the internal organs does not cause.
Levosin differs from Levomekol in composition. Levomekol contains only chloramphenicol and methyluracil. Ointment is produced in tubes of 40 g. Each package of Levomekol contains instructions for use, which indicate the main indications for using the ointment:
- Wounds with purulent contents, if the isolated pathogen is included in the activity spectrum of the drug;
- Accelerating the healing of wounds and burns of various etiologies;
- Treatment of inflammation of the nasal sinuses and middle ear.
Contraindications to the use of Levomekol are identical to the contraindications to the application of Levosin and include increased sensitivity reactions to the components of the composition of the drug. Adverse reactions are few and rarely occur in the form of urticaria-type rashes.
Since these drugs have similar basic pharmacological properties and indications, we can assume that Levosin is an analogue of Levomekol.
The method of application of Levomekol is also in many ways similar to the rules for applying Levocin. The preparation is applied on a sterile material (napkins, tampons, cotton balls) and the wound is filled with this material.
In surgical practice, Levomekol can be used to introduce active substances directly into the cavity containing pus. The duration of treatment with Levomekol is not less than a week.
Comparison of Levomekol and Levosin
After studying the basic parameters of medicines, it is easy to make a detailed comparison of Levomekol and Levosin. In general, the drugs are completely identical.
There is a slight difference in the composition – Levosin, in addition to the components common to Levomekol, also contains levomycetin. The content of chloramphenicol slightly expands the spectrum of activity of Levomekol, but, nevertheless, the indications for use in drugs are the same.
Both Levomekol and Levosin are popular among the people. The drugs have the same indications and contraindications for use, practically do not cause side effects, have no specific instructions.
Levomekol and Levosin can be used to disinfect purulent cavities through drainage tubes.
Levomekol and Levosin have been used in medical practice for a long time., therefore, there is a tendency to reduce the sensitivity of the bacterial flora to the components of these preparations. Microorganisms mutate, produce new proteins and become resistant to habitual antibiotics.
The effect from the use of Levomekol and Levosin is usually only in those patients who have not previously used these drugs to treat any purulent infections.
Possibility of sharing
Usually there is no need for the joint use of two antibacterial ointments with almost identical properties. The wound surface can be lubricated at the same time by Levosin and Levomekol, these medications do not possess antagonistic properties, act unidirectionally, do not enhance the effects of each other.
Before applying ointments, it is imperative that an initial surgical treatment of the wound be performed. After treatment and lubrication with Levosin and Levomekol, it is recommended to apply a sterile dressing.
Bandages should be changed at least twice a day until the healing of the purulent process.
Like all antibiotics, Levosin and Levomekol require compliance with the rules for taking antibacterial drugs:
- Use only as directed by the attending physician. Uncontrolled use of antibacterial drugs contributes to the development of microbial resistance. The more often antibiotics are used unreasonably, the more difficult it is to cure a really serious microbial infection in the future;
- Compliance with dosages and treatment. It is necessary to strictly adhere to the treatment regimen specified in the instructions for use or told by the doctor at the consultation. Under no circumstances should the antibiotic be discontinued earlier than in a week (for some drugs – 3-4 days);
- Intake of additional drugs that protect the internal organs. This item does not apply to Levomekol and Levosin. When taking systemic medicines, it is necessary to use probiotics, prebiotics to normalize the intestinal microflora. If you need to take toxic drugs, it is better to combine the use with hepato-, angi-, renoprotectors.
Levosin and Levomekol can be considered analogues of each other.. It should be remembered that both ointments have been used in medical and folk practice for a long time and uncontrolledly, therefore many microorganisms have developed resistance to the main pharmaceutical substances of these drugs.
Not all patients have an antimicrobial effect from applying ointments, but in any case, Levosin and Levomekol promote faster healing.
It is unreasonable to lubricate Levosin’s wound together with Levomekol, since both ointments act unidirectionally, do not enter the systemic circulation, do not potentiate each other’s effects. If there is evidence, choose one drug and undergo a full and sufficient course of treatment.