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Levofloxacin or Azithromycin: what is better and whether it is possible at the same time, compatibility

Pneumonia is one of the most common infectious causes of death on Earth. In this regard, doctors often face the question of what is better: Levofloxacin or Azithromycin in the treatment of severe inflammatory pathologies of the respiratory tract.

Drug selection

The choice of antibacterial agent is based on:

  • the possibilities of its impact on the alleged causative agent of the disease;
  • properties to penetrate and accumulate in the cellular tissues of the body;
  • data on its security;
  • the method of administration and dosing of the antibiotic;
  • price category of the drug.

However, it is rather difficult to compare Azithromycin and Levofloxacin. Azithromycin – a drug belonging to the group of macrolides, Levofloxacin – to the group of fluoroquinolones . Despite the fact that the drugs belong to different groups of antibiotics, they are equally widely used in the treatment of many diseases caused by pathogenic microorganisms.

Therefore, the comparison of drugs is not always correct.

Sometimes with severe inflammatory processes or complications, to enhance therapeutic efficacy, the doctor may recommend taking the drugs Azithromycin and Levofloxacin at the same time.

Azithromycin Description

Azithromycin – semisynthetic antibacterial drug of bacteriostatic action, belonging to the group of macrolides – azalides. It has a wide spectrum of action.

It shows itself well in the treatment of diseases provoked by development:

  • gonococcus;
  • streptococci;
  • staphylococcus;
  • spirochetes;
  • chlamydia;
  • mycoplasmas;
  • anaerobic microflora;
  • ureaplasma;
  • fungal lesions.

A huge number of drug analogues have been applied in the treatment of diseases caused by bacterial infections. These include: Sumamed, Azitroks, Ecomed, ZI-factor, Azimitsin, Sumatrolid Solyutab, Zytrotsin, Erythromycin, Clarithromycin, Azithromycin and many other antibacterial drugs.

However, antibiotic monotherapy is not always effective. According to clinical studies, the compatibility of Azithromycin with Levofloxacin is considered, for example, in the treatment of legionella infections.

Description of Levofloxacin

Levofloxacin – antibacterial drug belonging to the group of fluoroquinolones and having a broad spectrum of bactericidal effects. Used in the treatment of infectious and inflammatory pathologies caused by infection with microorganisms sensitive to levofloxacin.

Levofloxacin is active against gram-positive and gram-negative microorganisms, anaerobic, acid-resistant and atypical bacteria.

This antibiotic is rapidly absorbed in the gastrointestinal tract, it easily penetrates the cells of body tissues, reaching the maximum concentration in the blood within 1-2 hours after ingestion. Levofloxacin is compatible with macrolide drugs (with Azithromycin).

The effect of the drug can be reduced while taking drugs that reduce gastrointestinal motility.

Depending on the type of illness, doctors prescribe to take the drug once or twice a day in dosages of 250 or 500 mg, depending on the nature and severity of the infection. To achieve a more effective therapeutic effect (depending on the sensitivity of the suspected pathogen), the following medications may be recommended: Azithromycin and Levofloxacin at the same time.

Treatment regimens and the duration of the drug is determined by the attending physician depending on the clinical manifestations of the disease, the patient’s condition and the effectiveness of antibiotic therapy.

Vidal: https://www.vidal.ru/drugs/azithromycin__24064
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGu

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